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          Klemens J Hertel

          Professor, Microbiology & Molecular Genetics
          School of Medicine

          Chair, Microbiology & Molecular Genetics
          School of Medicine

          B.A., Colorado College
          PH.D., University of Colorado, Boulder

          ORCiD: 0000-0002-7560-9529

          Phone: (949) 824-2127
          Fax: (949) 824-8598
          Email: khertel@uci.edu

          University of California, Irvine
          B240B Med Sci I
          Mail Code: 4025
          Irvine, CA 92697

          Research Interests

          Alternative pre-mRNA splicing, regulation of gene expression, splicing regulation, bioinformatics, deep sequencing, Spinal Muscular Atrophy, human genetic disease, molecular therapy, stem cells, colon cancer

          Research Abstract

          With the completion of the human genome project, it has become clear that the sheer number of genes cannot account for the complexity of the human proteome.

          Among several proposed mechanisms, alternative pre-mRNA splicing is considered to be one of the most efficient and widespread avenues to generate multiple protein isoforms